Cayo Mambi, Cuba offers 1 beach perfect for sunbathing, surfing, swimming, and more. Cayo Mambi, Holguin, Cuba, is known for its proximity to the stunning beaches of Guardalavaca and the natural beauty of the Sierra Cristal National Park. The best time to travel to Cayo Mambi, Cuba, is from December to April, with average air temperatures around 75-85°F (24-29°C) and water temperatures around 77-82°F (25-28°C). Sandee provides detailed maps, photos, and reviews from fellow beachgoers to help you Choose Your Beach™ and plan your perfect beach vacation!