San Antonio del Sur, Cuba offers 2 beaches perfect for sunbathing, surfing, swimming, and more. San Antonio del Sur, Guantanamo, Cuba, is known for its proximity to the Alejandro de Humboldt National Park. The best time to travel to San Antonio del Sur, Cuba, is from December to April, with average air temperatures around 75-85°F (24-29°C) and water temperatures near 77-82°F (25-28°C). Sandee provides detailed maps, photos, and reviews from fellow beachgoers to help you Choose Your Beach™ and plan your perfect beach vacation!